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Yoichi Hirakata Selected Research

Diffuse panbronchiolitis

1/2007Telithromycin inhibits the number of viable bacteria but not lymphocyte accumulation in a murine model of chronic respiratory infection.
10/2003Clarithromycin inhibits overproduction of muc5ac core protein in murine model of diffuse panbronchiolitis.
9/2003Overproduction of MUC5AC core protein in patients with diffuse panbronchiolitis.
6/2003Role of elastase in a mouse model of chronic respiratory Pseudomonas aeruginosa infection that mimics diffuse panbronchiolitis.
4/2003[Effect of macrolide antibiotics on secretion of MUC5AC in murine model of diffuse panbronchiolitis and related diseases].
5/2002Effect of clarithromycin on chronic respiratory infection caused by Pseudomonas aeruginosa with biofilm formation in an experimental murine model.

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Yoichi Hirakata Research Topics

Disease

27Infections
01/2014 - 05/2002
15Pneumonia (Pneumonitis)
02/2013 - 05/2002
15Urinary Tract Infections (Urinary Tract Infection)
08/2006 - 08/2002
9Respiratory Tract Infections (Respiratory Tract Infection)
04/2009 - 09/2002
8Communicable Diseases (Infectious Diseases)
08/2008 - 10/2002
6Diffuse panbronchiolitis
01/2007 - 05/2002
4Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
01/2005 - 06/2002
2Tuberculosis (Tuberculoses)
03/2014 - 06/2003
2Liver Diseases (Liver Disease)
01/2010 - 05/2002
2Mycoses (Diseases, Fungus)
02/2009 - 07/2005
2Cross Infection (Nosocomial Infection)
06/2008 - 03/2003
2Pneumococcal Pneumonia
03/2007 - 11/2004
2Bacterial Infections (Bacterial Infection)
03/2007 - 09/2004
2Cryptococcosis
01/2007 - 09/2005
2Neoplasms (Cancer)
07/2004 - 07/2002
2Sepsis (Septicemia)
11/2002 - 08/2000
1Actinomycosis
08/2013
1Nervous System Diseases (Neurological Disorders)
02/2013
1Pharyngitis (Sore Throat)
03/2011
1Pneumococcal Infections
03/2010
1Invasive Fungal Infections
02/2009
1Systemic Inflammatory Response Syndrome (Sepsis Syndrome)
06/2008
1Hemorrhage
03/2007
1Bronchiectasis
02/2007
1Bacterial Pneumonia
01/2007
1Pneumoconiosis
11/2006
1Brain Abscess (Abscess, Brain)
11/2006
1Bronchopneumonia
09/2006
1Spotted Fever Group Rickettsiosis (Rickettsialpox)
01/2006
1Body Weight (Weight, Body)
01/2006
1Community-Acquired Infections
04/2005
1Kaposi Sarcoma (Kaposi's Sarcoma)
01/2005
1Chronic Obstructive Pulmonary Disease (COPD)
11/2004
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
07/2004
1Leukemia
07/2004

Drug/Important Bio-Agent (IBA)

20Anti-Bacterial Agents (Antibiotics)IBA
04/2009 - 05/2002
17Anti-Infective Agents (Microbicides)IBA
10/2007 - 08/2002
7Ciprofloxacin (Cipro)FDA LinkGeneric
08/2008 - 03/2003
6Proteins (Proteins, Gene)FDA Link
06/2010 - 07/2002
6Pharmaceutical PreparationsIBA
04/2009 - 10/2002
6MacrolidesIBA
04/2009 - 05/2002
6Clarithromycin (Biaxin)FDA LinkGeneric
11/2007 - 01/2002
4Levofloxacin (Levaquin)FDA Link
03/2011 - 10/2002
4Penicillins (Penicillin)FDA Link
04/2009 - 06/2004
4AntigensIBA
01/2007 - 03/2002
4VancomycinFDA LinkGeneric
09/2006 - 10/2002
3QuinolonesIBA
10/2007 - 12/2003
3Gatifloxacin (Zymar)FDA Link
10/2007 - 12/2003
3telithromycin (Ketek)FDA Link
02/2007 - 09/2002
2CytokinesIBA
03/2010 - 08/2000
2beta-Lactamases (beta-Lactamase)IBA
06/2008 - 01/2007
2Ethambutol (Myambutol)FDA LinkGeneric
11/2007 - 01/2002
2Ampicillin (Omnipen)FDA LinkGeneric
01/2007 - 01/2006
2DX 619IBA
09/2006 - 01/2006
2MucinsIBA
09/2004 - 09/2003
2DQ113IBA
12/2003 - 12/2003
2TeicoplaninIBA
12/2003 - 10/2002
2Linezolid (Zyvox)FDA Link
08/2003 - 10/2002
2Interferon-gamma (Interferon, gamma)IBA
06/2003 - 08/2000
1InterferonsIBA
03/2014
1Gentamicins (Gentamicin)FDA LinkGeneric
01/2014
116S Ribosomal RNAIBA
08/2013
1Serum AlbuminIBA
02/2013
1Cytotoxins (Cytolysins)IBA
06/2010
1Type III Secretion SystemsIBA
06/2010
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2010
1Monoclonal AntibodiesIBA
03/2010
1Cephalosporins (Cephalosporin Antibiotics)IBA
04/2009
1CelluloseIBA
02/2009
1C-Reactive ProteinIBA
06/2008
1ProcalcitoninIBA
06/2008
1RifamycinsIBA
11/2007
1Azithromycin (Zithromax)FDA LinkGeneric
11/2007
1Leukocyte Elastase (Neutrophil Elastase)IBA
03/2007
1Biocompatible Materials (Biomaterials)IBA
03/2007
1TitaniumIBA
03/2007
1Stainless Steel (Steel, Stainless)IBA
03/2007
1SodiumIBA
03/2007
1Secretory Proteinase Inhibitory ProteinsIBA
03/2007
1sivelestatIBA
03/2007
1Erythromycin (Erycette)FDA LinkGeneric
01/2007
1Adrenal Cortex Hormones (Corticosteroids)IBA
01/2007
1Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric
11/2006
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
09/2006
1CoagulaseIBA
01/2006
1FluoroquinolonesIBA
01/2006
1sitafloxacinIBA
01/2006
1Small Interfering RNA (siRNA)IBA
01/2006
1SulbactamFDA LinkGeneric
01/2006
1Imipenem Drug Combination Cilastatin (Primaxin)FDA Link
01/2006
1polyglucosanIBA
07/2005
1Viral DNAIBA
01/2005
1beta-LactamsIBA
11/2004

Therapy/Procedure

3Operative Surgical Procedures
06/2004 - 08/2002
2Therapeutics
01/2006 - 05/2002
2Indwelling Catheters (Indwelling Catheter)
10/2003 - 08/2002
1Renal Dialysis (Hemodialysis)
01/2010
1Lung Transplantation
02/2009
1Combination Drug Therapy (Combination Chemotherapy)
11/2007
1Orthopedic Procedures
03/2007